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β2-microglobulin functions as an endogenous NMDAR antagonist to impair synaptic function. Cell. 2023.

Metabolic reprogramming in astrocytes results in neuronal dysfunction in intellectual disability. Mol Psychiatry. 2022.

USP25 inhibition ameliorates Alzheimer’s pathology through the regulation of APP processing and Aβ generation. J Clin Invest. 2022.

SNX14 deficiency-induced defective axonal mitochondrial transport in Purkinje cells underlies cerebellar ataxia and can be reversed by valproate. Natl Sci Rev. 2021.

Trisomy 21-induced dysregulation of microglial homeostasis in Alzheimer’s brains is mediated by USP25. Sci Adv. 2021;7(1): eabe1340. PMID: 33523861

Imaging of individual transcripts by amplification-based single-molecule fluorescence in situ hybridization. N Biotechnol. 2021;61:116-123. PMID: 33301924

RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation. Cell Death Differ. 2021;28(1):337-348. PMID: 32908202

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Visualization of individual microRNA molecules in fixed cells and tissues using target-primed padlock probe assay

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The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability. PLoS Biol. 2019;17(12): e3000525. PMID: 31841517

Novel KCNJ10 Compound Heterozygous Mutations Causing EAST/SeSAME-Like Syndrome Compromise Potassium Channel Function. Front Genet. 2019;10:912. PMID: 31781151

A de novo SCN8A heterozygous mutation in a child with epileptic encephalopathy: a case report. BMC Pediatr. 2019;19(1):400. PMID: 31672125

Snx27 Deletion Promotes Recovery From Spinal Cord Injury by Neuroprotection and Reduces Macrophage/Microglia Proliferation. Front Neurol. 2018;9:1059. PMID: 30619032

RPS23RG1 Is Required for Synaptic Integrity and Rescues Alzheimer's Disease-Associated Cognitive Deficits. Biol Psychiatry. 2018. pii: S0006-3223(18)31782-7. PMID: 30292394

The Retromer Complex and Sorting Nexins in Neurodegenerative Diseases. Front Aging Neurosci. 2018;10:79. PMID: 29632483

Intracellular trafficking of TREM2 is regulated by presenilin 1. Exp Mol Med. 2017;49(12):e405. PMID: 29611543

TREM2 Promotes Microglial Survival by Activating Wnt/β-catenin Pathway. J Neurosci. 2017;37(7):1772-1784. PMID: 28077724

Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases. Front Aging Neurosci. 2016;8:303. PMID: 28018215

SNX27 Deletion Causes Hydrocephalus by Impairing Ependymal Cell Differentiation and Ciliogenesis. J Neurosci. 2016;36(50):12586-12597. (co-corresponding author) PMID: 27974614

SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein. J Neurosci. 2016;36(30):7996-8011. PMID: 27466343

Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice. Neuropharmacology. 2016;108:179-192. PMID: 27114256

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis. Neuron. 2015;87(5):963-75. PMID: 26335643

Biallelic mutations in SNX14 lead to a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015 2015;47(5):528-34. PMID: 25848753

Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity. Cell Rep. 2014;9(3):1023-33. PMID: 25437557

Dysregulation of protein trafficking in neurodegeneration. Mol Neurodegener. 2014;9(1):31. PMID: 25152012

Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction via modulation of glutamate receptor recycling in Down's syndrome. Nat Med. 2013;19(4):473-80. PMID: 23524343

Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing. Mol Neurodegener. 2012; 7(30). PMID: 22709416

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